Disease-information
BMJ Open: Published, October, 2023This study aimed to investigate the
potential association between PPI use and kidney stones by analysing National
Health and Nutrition Examination Survey (NHANES) data from 2007 to 2018. TAKE-HOME MESSAGEThe authors
of this large US-based cross-sectional study found that proton-pump inhibitor
(PPI) use was asso...
American Journal of Orthodontics and Dentofacial Orthopedics: Published: August
29, 2023TAKE-HOME MESSAGEThis study
showed that, in patients with fixed orthodontic appliances, twice weekly use of
0.12% chlorhexidine (CHX) mouthwash reduced the plaque, gingival, and gingival
bleeding indexes when evaluated at 15, 30, and 60 days of protocol
imp...
JAMA: The Journal of the American Medical AssociationThe authors investigated different
oral antifungal medications used to treat toenail fungal infections.TAKE-HOME MESSAGECompared
with placebo, high-quality evidence supports better clinical (ie, normal
appearance of the toenail) and mycological (negative culture, microscopy, or
both) results...
There has been a significant
increase in the incidence of chronic, relapsing, recurrent cases of superficial
dermatophytosis in India that are also often unresponsive to conventional drugs
and doses of recommended antifungal treatment. Almost 15– 20% of the outpatient
department cases are those of chronic dermatophytosis. Recurrences and relaps...
What is Disease X?According to the World Health
Organization (WHO), “Disease X represents the knowledge that a serious
international epidemic could be caused by a pathogen currently unknown to cause
human disease.According to a UK health expert,
Disease X could lead to another pandemic more lethal than Covid-19 and could
claim at least 50 mill...
Journal of Diabetes and its Complications: August 2023Nearly one out of three individuals will develop a
psychiatric disorder during their life. Severe psychiatric disorders are
associated with higher mortality rates, with 10–20 life-years lost compared to
individuals without a severe psychiatric disorderSeveral psychiatric disorders are li...
Mycoses Journal: Published on April 2021Dermatomycoses of zoophilic origin,
especially those caused by Trichophyton mentagrophytes, often pose considerable
therapeutic problems. This is reflected in the growing number of strains of
this species with resistance to terbinafine caused by a mutation in the
squalene epoxidase (SQLE) gene. TAKE HOME...
Diabetes Care Journal (ADA): August, 2023Early identification of patients
with type 2 diabetes who are at risk of kidney disease progression is
particularly important in the context of new glucose-lowering medications such
as sodium-glucose cotransporter 2 (SGLT2) inhibitor (Dapagliflozin, Canagliflozin,
Empagliflozin, Ertugliflozin) that can m...
International Journal of Clinical Obstetrics and Gynecology: Published 2021Abnormal uterine bleeding is defined
as any type of bleeding that is abnormal in volume, frequency, duration and
periodicity. Frequent complaints include heavy and prolonged menstrual
bleeding with or without pain, passage of clots, fatigue and lethargy. AUB is...
JAMA Psychiatry: August, 2022The postpartum period is critical
for mothers, children, and families, and approximately 10% to 15% of new
mothers experience postpartum depression (PPD), one of the most common
complications related to childbirth.PPD ranges from mild to severe
episodes and includes similar symptoms as major depression outside...
TAKE HOME MESSAGERequests
for thyroid tests are increasing, although in many cases clinical need is not
evident.If thyroid
dysfunction is suspected, measuring TSH alone is recommended as the first step.
Test T4 only when TSH is abnormal.Ultrasound
should be considered for patients with thyroid dysfunction and goitre (enlarged
thyroid) or palp...
PubMed Central: November, 2022Tinea versicolor is a common superficial fungal infection of
the skin with various clinical manifestations. This review aims to familiarize
physicians with the clinical features, diagnosis and management of tinea
versicolor.Tinea versicolor is caused by Malassezia species,
notably M. globosa, M....
