Disease-information

Short versus Long-Term Antibiotic Prophylaxis in Cesarean Section
Cesareans delivery is the most common risk factor for postpartum maternal infections, which occurs at a rate of 18%–38%. Factors that have been associated with an increased risk of infection among women who have a cesarean delivery include emergency cesarean section, labor and its duration, ruptured membranes and the duration of rupture, t...
Amoxicillin plus Clavulanic Acid VS Amoxicillin in the Treatment of Community Acquired Pneumonia in Children
Community-acquired pneumonia (CAP) is a significant cause of respiratory morbidity and mortality in children, especially in developing countries. Worldwide, CAP is the leading cause of death in children younger than five years. Clinical assessment requires careful evaluation of clinical features, severity, and evidence of complications....
Guidelines on the Management of Eosinophilic Oesophagitis in Children and Adults
The British Medical Journal (BMJ): British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelineThese joint consensus guidelines from the British adult and paediatric gastroenterology societies utilize the GRADE methodology to make recommendatio...
Guidelines on the Diagnosis of Eosinophilic Oesophagitis in Children and Adults
The British Medical Journal (BMJ): British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines Eosinophilic oesophagitis is a condition characterised by symptoms of dysphagia and/or food impaction in adults, and feeding problems, abdominal...
The safety of Amoxicillin and Clavulanic acid use during the first trimester of Pregnancy
The British Pharmacological Society Journal: Published: 05 September 2019 Penicillin’s are widely used during pregnancy for various bacterial infectious indications. Amoxicillin, rapidly crosses the placenta following absorption to the bloodstream, It is prescribed both as a sole medicine as well as in combination with clavulanic acid mos...
The Effect of the COVID-19 Pandemic on Urine Culture Results and Resistance to Antibiotics
Urinary tract infections (UTIs) represent a common pathology among female patients, leading to overprescribing antibiotics, globally. The emergence of the COVID-19 pandemic has dramatically increased the incidence of this particular viral pneumonia with secondary bacterial superinfection, resulting in continuous therapeutic or prophylactic...
Antacid & Alginate is more effective than antacid in controlling post-prandial oesophageal acid exposure in GERD patients
Heartburn is a cardinal symptom of gastro-oesophageal reflux disease (GERD) and is among the most common patient complaints encountered by physicians. TAKE HOME MESSAGE: This study compared the effect of Antacid & Alginate Liquid to an antacid in controlling post-prandial acid reflux in GERD patients. The current investigation demons...
Amoxicillin-Clavulanic Acid Empirical Oral Therapy for Management of Children with Acute Haematogenous Osteomyelitis
PubMed Central: Published on 2020 August AHOM was defined as any bone infection with a period between symptoms onset and diagnosis < two weeks. AHOM was defined complicated in the presence of sepsis, septic shock, arthritis, cellulitis, sub-periosteal or muscle abscess, deep vein thrombosis pathological fracture, septic emboli or hosp...
Long term impact of prophylactic antibiotic use before incision VS after cord clamping on Children by caesarean section
The British Medical Journal (BMJ): Published 17 May 2022 Compared with vaginal delivery, caesarean section carries a substantially increased risk of maternal postpartum infections. This risk can be reduced by routine provision of prophylactic antibiotics. Evidence from randomized controlled trials shows that antibiotics are more effe...
An update on drug-drug interactions associated with proton pump inhibitors
Expert Opinion on Drug Metabolism & Toxicology Journal: Published on: 11 Jul 2022 Proton pump inhibitors (PPIs) are widely prescribed for the treatment of gastric acid-related disorders and the eradication of Helicobacter pylori. In addition, they are routinely prescribed for the prevention of gastrointestinal bleeding in patients receiv...
Effect of a combination of Telmisartan and Amlodipine on patients with Hypertension
Hypertension is considered a major health problem around the world. It’s associated with increasing risk of mortality due to its complication which has a great impact on patient’s life quality. Chronic uncontrolled hypertension is a significant risk factor for cardiovascular mortality and morbidity, strokes, heart failure, and renal fai...
Dienogest and the Risk of Endometriosis Recurrence Following Surgery
Journal of Minimally Invasive Gynecology: Published on December 2020 Endometriosis is a common condition affecting women of reproductive age, often presenting with pelvic pain and infertility. In addition to significantly impacting a woman’s quality of life, the treatment of endometriosis carries a considerable economic burden. TAKE...