Disease-information

European Heart Journal: September, 2022Cardiovascular (CV) disease (CVD) is the leading cause of morbidity and mortality worldwide, despite continuous improvement of medical treatment, diagnosis, and risk factor control. It has been clearly demonstrated that statin therapy confers significant mortality and morbidity benefits in both the primary...
The Lancet: Published on September, 2022A promising malaria vaccine was up to 80% effective at preventing the disease in young children who received a booster shot at one year following a primary three-dose regime maintained high efficacy against malaria, and continued to meet the World Health Organization’s Malaria Vaccine Technology Roadmap g...
Journal of the American Heart Association (AHA): Published on November, 2022Sleep, alongside diet and physical activity (PA), is one of the 3 pillars of health, but unlike other health behaviors, healthy sleep is not included in the American College of Cardiology/American Heart Association (AHA) cardiovascular disease (CVD) prevention guideline...
Nature Medicine: Published on November, 2022Obesity is a chronic, relapsing disease with a substantial morbidity, mortality, and healthcare burden. Drug interventions for the treatment of obesity provide a potential valuable adjunct to lifestyle interventions, which often achieve only limited weight loss that is difficult to maintain. Semagluti...
The Journal of Clinical Endocrinology and Metabolism (JCEM): Published On October, 2022Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and type 2 diabetes (T2D), causing substantial burden from hepatic and extrahepatic complications.TAKE-HOME MESSAGEThis review discusses practical approaches to the management of patients wit...
Journal of the American College of Cardiology: Published on December, 2022Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified.The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifi...
MIDDLE EAST JOURNAL OF FAMILY MEDICINE: Published on November, 2022A Systematic Review and Meta-AnalysisEndometriosis is a chronic, estrogen-dependent disease that affects 10-15% of women in their reproductive age. It is characterized by the presence of endometriallike tissues outside the uterine cavity that induce chronic inflammation, ovarian...
Journal of Clinical Medicine: Published on November 2022Periodontitis is an inflammatory disease of multifactorial origin, characterized by periods of exacerbation and remission. The main etiological factors for the disease include gram-negative anaerobic bacteria and a variety of facultative bacteria that reside in the subgingival biofilm.Var...
JAMA Pediatrics: Published on November 2022A Systematic Review and Meta-analysisTAKE-HOME MESSAGEAre shorter courses of antibiotics as good as longer courses?This systematic review and meta-analysis assessed whether shorter courses of antibiotics are noninferior to longer courses of antibiotics for nonsevere community-acquired pneumonia (CAP) in...
JAMA Pediatrics: Published on November 2022A Systematic Review and Meta-analysisTAKE-HOME MESSAGEAre shorter courses of antibiotics as good as longer courses?This systematic review and meta-analysis assessed whether shorter courses of antibiotics are noninferior to longer courses of antibiotics for nonsevere community-acquired pneumonia (CAP) in...
Diabetes Care: Published on December 2022With the numbers of people with type 2 diabetes rising worldwide, dietary modifications provide an essential therapeutic approach for blood glucose, weight, and cardiovascular risk-factor management. Intermittent fasting (IF) has emerged as an alternative to classic daily caloric reduction. The approache...
The Lancet: Published on January, 2023The appropriate duration of postoperative antibiotics for complex appendicitis is unclear. The increasing global threat of antimicrobial resistance warrants restrictive antibiotic use, which could also reduce side-effects, length of hospital stay, and costs.TAKE-HOME MESSAGEThis pragmatic, open-label, rando...